Our research is focused on functional and structural characterization of an unusual class of transcription factors that regulate polysaccharide utilization in Bacteroides. Dietary fiber is an important carbon source for gut bacteria and it impacts the composition of the gut microbiome. In Bacteroides, dozens of gene clusters encoding protein systems necessary for metabolism of specific complex carbohydrates are colocalized into polysaccharide utilization loci, or PULs. Many PULs are regulated by Hybrid Two-Component Systems (HTCSs) in which the transmembrane sensor histidine kinase and response regulator transcription factor of canonical TCSs are fused into a single protein. HTCS regulation is central to the important balance between degradation of dietary fiber and host glycans that form the intestinal mucus layer.

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Research

NIH T32 grant renewed for Rutgers Graduate Training Program in Biotechnology
September 4, 2025
NIH T32 grant renewed for Rutgers Graduate Training Program in Biotechnology

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Ann Stock named ASBMB Fellow
February 17, 2025
Ann Stock named ASBMB Fellow
ASBMB

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Ann Stock appointed as the ASBMB representative to the Board of Directors of the Coalition for Life Sciences
February 10, 2025
Ann Stock appointed as the ASBMB representative to the Board of Directors of the Coalition for Life Sciences

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Ann Stock receives F. Marion Hulett Award
January 22, 2025
Ann Stock receives F. Marion Hulett Award

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Congratulations Samantha Brokaw - recipient of the Henry Rutgers Scholar Award
May 9, 2023
Congratulations Samantha Brokaw - recipient of the Henry Rutgers Scholar Award

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Ann Stock receives 2022 Waksman Award from the Theobald Smith Society
May 26, 2022
Ann Stock receives 2022 Waksman Award from the Theobald Smith Society

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Ann Stock received NSF Award for project titled "Collaborative Research: Chemotactic signaling in Sinorhizobium meliloti symbiotic plant host interaction"
September 7, 2021
Ann Stock received NSF Award for project titled "Collaborative Research: Chemotactic signaling in Sinorhizobium meliloti symbiotic plant host interaction"

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Congratulations Libby Helfant - recipient of the Henry Rutgers Scholar Award
May 7, 2021
Congratulations Libby Helfant - recipient of the Henry Rutgers Scholar Award

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Conversations with CABM Director: An interview with Dr. Ann Stock
January 6, 2021
Conversations with CABM Director: An interview with Dr. Ann Stock
YouTube

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