Our research is focused on functional and structural characterization of an unusual class of transcription factors that regulate polysaccharide utilization in Bacteroides. Dietary fiber is an important carbon source for gut bacteria and it impacts the composition of the gut microbiome. In Bacteroides, dozens of gene clusters encoding protein systems necessary for metabolism of specific complex carbohydrates are colocalized into polysaccharide utilization loci, or PULs. Many PULs are regulated by Hybrid Two-Component Systems (HTCSs) in which the transmembrane sensor histidine kinase and response regulator transcription factor of canonical TCSs are fused into a single protein. HTCS regulation is central to the important balance between degradation of dietary fiber and host glycans that form the intestinal mucus layer.

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Research

Congratulations Samantha Brokaw - recipient of the Henry Rutgers Scholar Award
May 9, 2023
Congratulations Samantha Brokaw - recipient of the Henry Rutgers Scholar Award

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Ann Stock receives 2022 Waksman Award from the Theobald Smith Society
May 26, 2022
Ann Stock receives 2022 Waksman Award from the Theobald Smith Society

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Ann Stock received NSF Award for project titled "Collaborative Research: Chemotactic signaling in Sinorhizobium meliloti symbiotic plant host interaction"
September 7, 2021
Ann Stock received NSF Award for project titled "Collaborative Research: Chemotactic signaling in Sinorhizobium meliloti symbiotic plant host interaction"

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Congratulations Libby Helfant - recipient of the Henry Rutgers Scholar Award
May 7, 2021
Congratulations Libby Helfant - recipient of the Henry Rutgers Scholar Award

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Conversations with CABM Director: An interview with Dr. Ann Stock
January 6, 2021
Conversations with CABM Director: An interview with Dr. Ann Stock
YouTube

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Rutgers NIH Biotechnology Training Program Renewed
November 6, 2020
Rutgers NIH Biotechnology Training Program Renewed

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Distinguished Professor Ann Stock honored as a member of the National Institute of General Medical Sciences (NIGMS) Training and Workforce Development Subcommittee B
July 9, 2020
Distinguished Professor Ann Stock honored as a member of the National Institute of General Medical Sciences (NIGMS) Training and Workforce Development Subcommittee B

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Congratulations Ann Stock - promoted to rank of Distinguished Professor
July 7, 2020
Congratulations Ann Stock - promoted to rank of Distinguished Professor

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