2020 CABM Virtual Retreat
9:00 AM Welcome (Marty Blaser)
9:05 AM Session 1: Regulation & Quantitation
Nicholas Pontillo (Edery Lab) “Daywake adjusts daily wake-sleep levels to minimize survival threats”
Rong Gao (Stock Lab) “A balancing act in transcription regulation: titration of transcription factor activity by DNA binding sites”
Cindy Lin (Rabson Lab) “PDCD2: A novel regulator of ribosome biogenesis”
Dhiman Maitra (Omary Lab) “Specific structures of protoporphyrin-IX modulate its protein aggregation ability via differential oxidation and protein binding”
David Sleat (Lobel Lab) “An introduction to quantitative proteomics using isobaric labeling”
10:20 AM Break
10:35 AM Session 2: Design & Exploitation
Elliot Campbell (Anderson Lab) “Modifying protein conformational dynamics to improve the adaptive immune response”
Hiroko Nobuta “Gene engineering towards oligodendrocyte regenerative medicine”
Srijata Sakar (Gélinas Lab) “Exploiting the ubiquitin-proteasome system to target signaling pathways important for HIV-1 latency”
Alexander Valvezan “Exploiting metabolic dependencies in tumors”
Saroj Poudel (Nanda Lab) “Design of a primordial hydrogenase”
11:50 AM 2020 SURE Program (Natalie Losada)
12:00 PM Lunch Break
1:00 PM Poster Presentations
Zhan Gao (Blaser) “Effects of antibiotics on the microbiome of healthy human volunteers (MIME study)”
Jesse Ames (Blaser) “Effects of antibiotics on estrogen metabolism in the Estrobolome”
Gabe Villegas (Edery Lab) “Biochemical characterization of the DAYWAKE anti-siesta protein”
Menghan Liu (Blaser Lab) “Multi ‘omics’ analyses of intestinal oxalate metabolism”
Meifan Zhang (Blaser Lab) “Inactivation of trypsin by the intestinal microbiota”
Jing Shen (Gélinas Lab) “Role of coactivator and splicing factor CAPER alpha/RBM39 in breast cancer”
Sandra Yin (Blaser Lab) “Understanding the biological roles of SAA”
1:45 PM Break
2:00 PM Session 3: Health & Disease
Anat Kreimer “Coupling functional genomics techniques with computational modeling to understand gene regulation in health and disease”
Fang Liu “CD44 inhibits the transition of ductal carcinoma in situ to invasive breast carcinoma”
Xuesong Zhang (Blaser Lab) “Microbiota-host interaction in mouse models of type 1 diabetes”
Aaron Milstein “Neural circuit mechanisms of rapid and reversible memory”
Ashima Chopra (Arnold Lab) “X-ray crystallographic fragment screening and covalent molecule screening of HIV-1 reverse transcriptase”
3:15 PM Break
3:30 PM Session 4: COVID-19 Research at CABM
Sanjay Dey (Arnold Lab) “Functional and biophysical characterization of SARS-CoV-2 polyproteins and proteins expressed in and purified from bacteria”
Masayori Inouye “Covid-19 RNA: its unique content of specific 7-base sequences”
Douglas Pike (Nanda Lab) “De novo design of SARS-CoV-2 peptide inhibitor”
Stephen Anderson “Hurdles faced by COVID-19 vaccines currently under development:How antigen engineering might help meet those challenges”
Martin Blaser “Update on the Rutgers Corona Cohort (RCC)”
4:45 PM Closing Comments (Marty Blaser)