Education
M.D. Nanjing Medical University 1985
Bio
Dr. Zhan Gao has been involved in microbiome research for more than 20 years, since she first used powerful molecular methods to determine the composition of bacterial populations on the skin and is currently involved in most of the microbiome research in Dr. Blaser’s lab. Her research includes the use of mouse models to study the effects of antibiotics on obesity, metabolic and immune disorders, the molecular biology of the microbiome in skin, gastric, intestinal and renal disorders, the role of antibiotic-induced microbiome perturbations in the early development of autism spectrum disorders and Alzheimer's disease, as well as microbial, immune and metabolic perturbations by antibiotics in young adults.
Research Focus
Microbiome perturbation caused by Antibiotics; interactions between microbes and host
1.
Alhamwe B, Gao Z, Alhamdan F, et al. Intranasal administration of Acinetobacter lwoffii in a murine model of asthma induces IL-6-mediated protection associated with cecal microbiota changes. Allergy. 2023;78(5):1245-1257. doi:10.1111/all.15606.
1.
Borbet TC, Pawline M, Zhang X, et al. Influence of the early-life gut microbiota on the immune responses to an inhaled allergen. Mucosal immunology. 2022;15(5):1000-1011. doi:10.1038/s41385-022-00544-5.
1.
He L, Wang C, Hu J, et al. ARZIMM: A Novel Analytic Platform for the Inference of Microbial Interactions and Community Stability from Longitudinal Microbiome Study. Frontiers in genetics. 2022;13:777877. doi:10.3389/fgene.2022.777877.
1.
Garshick MS, Nikain C, Tawil M, et al. Reshaping of the gastrointestinal microbiome alters atherosclerotic plaque inflammation resolution in mice. 2021;11(1):8966+. doi:10.1038/s41598-021-88479-y.
1.
Volkova A, Ruggles K, Schulfer A, Gao Z, Ginsberg S, Blaser MJ. Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression. iScience. 2021;24(7):102797. doi:10.1016/j.isci.2021.102797.