Education

B.S. Molecular Cell Biology, Tehran University, 2004
M.S. Molecular Cell Biology, Shiraz University, 2007
Ph.D. Genes and Development Program, Max Planck Institute for Biophysical Chemistry, Goettingen University 2013
Postdoctoral fellow, Max Planck Institute for Biophysical Chemistry, Goettingen University, 2014
Postdoctoral fellow, Boston Children’s Hospital, Harvard Medical School, 2020

Bio

Mehdi Pirouz is an Assistant Professor in the Department of Biochemistry and Molecular Biology at Rutgers Medical School and a Resident Faculty member of the Center for Advanced Biotechnology and Medicine in New Jersey. Dr. Pirouz graduated from Max Planck Institute for biophysical chemistry in Goettingen, Germany, where he studied the role of chromatin-binding proteins in mouse development and stem cells. For his postdoctoral training, Dr. Pirouz join the laboratory of Dr. Richard Gregory at Boston Children’s Hospital, Harvard Medical School, to study the role or RNA metabolism in stem cells and diseases. The focus of Dr. Pirouz’ laboratory is to study noncanonical mRNA translation pathways contributing to cellular homeostasis, stemness and differentiation.

Research Focus

Understanding the role of RNA metabolism in Stem Cells, Development, and Disease

Assistant Professor of Biochemistry and Molecular Biology, RJWMS

K01 Transition Award, NIH-NIDDK (2020-2023)

Postdoctoral fellowship, Manton Center for Orphan Disease Research (2018-2020)

PhD fellowship, Max Planck Society (2009-2013)

Pirouz M, Wang C-H, Liu Q, et al. The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis. Nature communications. 2020;11(1):2619. doi:10.1038/s41467-020-16418-y.
Pirouz M, Munafò M, Ebrahimi A, Choe J, Gregory R. Exonuclease requirements for mammalian ribosomal RNA biogenesis and surveillance. Nature structural & molecular biology. 2019;26(6):490-500. doi:10.1038/s41594-019-0234-x.
Pirouz M, Du P, Munafò M, Gregory R. Dis3l2-Mediated Decay Is a Quality Control Pathway for Noncoding RNAs. Cell reports. 2016;16(7):1861-73. doi:10.1016/j.celrep.2016.07.025.